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Dr. Lamy

Professional Organizations

  • Canadian Medical Association Ontario
  • The College of Physicians and Surgeons of Ontario

Research Interests

Dr. Lamy has been involved in clinical research since the beginning of his career and has collaborated with many research groups and pharmaceutical and devices companies around the world. His interests are centred on large, randomized controlled trials (RCT) in cardiac surgery and health economics.

His most significant contribution in cardiac surgery is the CORONARY trial for which he received a large grant from the Canadian Institute of Health Research in 2007. CORONARY is a large multi centred randomized trial of off-pump CABG surgery versus on-pump CABG surgery. CORONARY has recruited and randomized 4,752 patients from 79 centres in 19 countries. The results were presented at the Late Breaking Clinical Trials at the American College of Cardiology meeting in 2012 and 2013 and were published in the New England Journal of Medicine in 2012 and 2013. The trial recently finished with a follow-up of five years. These final results were published in the New England Journal of Medicine October 2016. 

Over the years, Dr. Lamy has also accumulated a large database of cardiovascular costs in about 40 countries and produced economic analyses of major trials such as HOPE, CURE, ACTIVE-A, ORIGIN, ONTARGET, TIMACS, and CORONARY. He is also contributing with on-going trials such as HOPE-3, COMPLETE, and HIP ATTACK.

Dr. Lamy is currently involved with the VISION-Cardiac surgery trial, a prospective analysis of 15,000 patients around the world to determine the cut-off value and prognostic factor of the new generation of troponin essays after cardiac surgery 

Featured Publications

  • Lamy A, Devereaux PJ, Prabhakaran D, Taggart DP, Hu S, Straka Z, Piegas LS, Avezum A, Akar AR, Lanas Zanetti F, Jain AR, Noiseux N, Padmanabhan C, Bahamondes JC, Novick RJ, Tao L, Olavegogeascoechea PA, Airan B, Sulling TA, Whitlock RP, Ou Y, Gao P, Pettit S, Yusuf S, CORONARY Investigators. Five-Year Outcomes after Off-Pump or On-Pump Coronary Artery Bypass Grafting. N Engl J Med. 2016 Oct 23 doi:10.1056/nejmOA1601564.

  • Lamy A, Tong W, Devereaux PJ, Gao P, Gafni A, Singh K, Taggart D, Straka Z, Akar AR, Piegas L, Ou Y, Yusuf S. The Cost Implications of Off-Pump Versus On-Pump Coronary Artery Bypass Graft Surgery at One Year. Ann Thorac Surg:2014 Nov;98(5):1620- 5 PMID:25261272. 

  • Lamy A, Devereaux PJ, Prabhakaran D, Taggart D, Hu S, Paolasso E, Straka Z, Piegas L, Akar A, Jain A, Noiseux N, Padmanabhan C, Bahamondes J, Novick R, Vaijyanath P, Reddy S, Tao L, Olavegogeascoechea P, Airan B, Sulling TA, Whitlock R, Ou Y, Ng J, Chrolavicius S, Yusuf S, The CORONARY Investigators Off-Pump or On-Pump Coronary-Artery Bypass Grafting at 30 Days. N. Eng Med.  2012 Apr 19;366(16):1489-97.

  • Lamy A, Devereaux PJ, Prabhakaran D, Hu S, Piegas LS, Straka Z, Paolasso E, Taggart D, Lanas F, Akar AR, Jain A, Noiseux N, Ou Y, Chrolavicius S, Ng J, Yusuf S. Rationale and design of the Coronary Artery Bypass Grafting Surgery Off or On Pump Revascularization Study: A large international randomized controlled trial in cardiac surgery. Am Heart J. 2012 Jan; 163 (1) 1-6. 

Education

  • University of British Columbia              
    Master’s Degree MHSc., Clinical epidemiology                                                                       
  • University of British Columbia               
    Diploma, FRCSC, Cardiothoracic surgery 

  • Laval University 
    Diploma, FRCSC, General surgery
    Doctorate, MD

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