Dr. Laurie Doering is a Professor in the Department of Pathology and Molecular Medicine with a PhD in developmental neuroscience. He completed post-doctoral training at McGill University and the Montreal Neurological Institute and currently heads the Neuroscience division in the Medical Sciences Graduate Program. He has extensive training and expertise in stem cell biology, tissue culture, neurotransplantation, molecular imaging and animal models of nervous system dysfunction. He has generated collaborative research papers on aspects of neurological cell therapy with scientists in McMaster University, Canada, the United States and Europe. He is the current Editor of Protocols for Neural Cell Culture.
Dr. Doering directs a basic research program that studies the cell biology of neural stem cells where they isolate stem cells from the mouse and rat brain and expand the cells in culture. The growth and differentiation of the stem cells are characterized before transplantation into animal models of Parkinson's and the Fragile-X syndrome. The stem cells are used as a means of potential cell therapy to replace missing proteins and restore function in specific pathways of the animal models. An additional line of work examines the role of a protein phosphatase in neural stem cell formation and neuronal growth.
tissue culture, transplantation of stem cells into the CNS, immunocytochemistry, fluorescence, confocal miscroscopy and imaging.