Broadly, Dr. Bhandari’s vision for his research program includes the identification and dissemination of novel therapies with high quality collaborative research practices to improve the lives of persons with musculoskeletal trauma. Three core research themes are operationalized primarily by the conduct of multi-national large randomized trials and large observational cohort studies.
Existing Programs:
Theme I: Road traffic and associated high energy trauma
- To explore the factors associated with major outcomes following fracture treatment in low-middle income countries
- To compare optimal wound irrigation strategies for the initial treatment of severe open fracture wounds
Theme II: Intentional injuries in women (violence against women, domestic violence)
- To examine health outcomes in women experiencing fractures from domestic violence
- To develop an educational toolkit to aid physicians in the optimal care of abused women presenting to fracture clinics across Canada and internationally
Theme III: Osteoporotic and low energy trauma in the elderly
- To assess the relative impact of hip replacement strategies (total hip versus hemi-arthroplasty) on major health outcomes in individuals with femoral neck fractures
- To assess the relative impact of hip fixation strategies (multiple screws versus sliding hip screws) on major health outcomes in individuals with femoral neck fractures
Ongoing Trials and Observational Cohorts
INternational ORthopaedic MUlticenter Study in Fracture Care (INORMUS): A 40, 000 patient, prospective cohort, learn more at : www.inormus.ca
A Program of Randomized trials to Evaluate Pre-operative antiseptic skin solutions In Orthopaedic (PREP-IT): Two partnered trials aiming to enroll 10,000 patients with fractures (PCORI and US Dept of Defense funded) Learn more at: www. https://www.prepittrial.com/
Fixation Alternatives In The Treatment of Hip Fractures: (FAITH-2) Multinational RCT-CIHR funded/NIH Funded: A pilot feasibility study of 100 patients to explore fracture fixation in young adults
Hip fracture Evaluation with Alternatives of Total hip arthroplasty vs Hemiarthroplasty (HEALTH): Multinational RCT –A large, multinational trial (CIHR funded/NIH Funded) Learn more at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954961/
Hip ATTACK Multinational Randomized Trial – Timing of surgery in hip fractures learn more: https://clinicaltrials.gov/ct2/show/NCT02027896; The pilot RCT was published in http://www.cmaj.ca/content/186/1/E52
Prevalence of Abuse and Intimate Partner Violence Surgical Evaluation (PRAISE-2): Multinationa Cohort Study : A Pilot feasibility cohort
Knowledge Translation: EDUCATE program (CIHR Funded) : Learn more http://www.ipveducate.com/the-educate-training-program
The EDUCATE program was designed using the best available evidence by experts in the field of orthopaedics, intimate partner violence, and education. It uses a multi-faceted approach to deliver training, including: an in-person presentation, videos, case sharing, and interactive discussions. It also includes three optional online modules that can be completed by individuals who desire additional training.
New Programs for 2019
Theme IV: Degenerative Disease
- Novel treatments inthe management of Osteoarthritis of the hip and knee joints
- Preventive trials on major complications following hip and knee arthroplasty