Dr. Sheila Sprague is a clinical researcher with expertise in the design and conduct of large randomized controlled trials, observational studies, systematic reviews, and scoping reviews. She obtained a Doctorate Degree in Medical Science from the University of Amsterdam and a Master of Science Degree in Health Research Methodology from McMaster University. She became a Faculty Member with the Department of Surgery in 2014 and an Associate Faculty Member in the Department of Health Research Methods, Evidence, and Impact in 2017. In addition to her faculty appointments, Dr. Sprague serves as the Research Director at the Centre for Evidence-Based Orthopaedics at McMaster University. Her research interests include optimizing the fracture clinic to assist women experiencing intimate partner violence and improving outcomes in fracture patients. Dr. Sprague is an expert in clinical trial implementation. She is a co-principal investigator for the PREP-Program, which includes two multi-centre cluster crossover trials that will determine the most effective pre-operative skin preparation solution in fracture patients. Together with her colleagues, Dr. Sprague has secured over $21 million in funding for these research initiatives since obtaining her faculty appointment. Throughout her career, Dr. Sprague has authored over 200 peer-reviewed publications, 14 book chapters, and 150 conference abstracts and posters. These include publications in top medical journals such as the Lancet, New England Journal of Medicine, and British Medical Journal.