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Canadian Orthopaedic Trauma Society Studies



​Dr. ​Brad Petrisor


Dr. ​Herman Johal


Dr. ​Bill Ristevski

The Canadian Orthopaedic Trauma Society (COTS) trials are a series of randomized prospective multicentre trauma research studies being conducted in Canada. Listed below are several COTS studies that McMaster University is participating in as a recruiting site.



INSURT is a multi-site randomized control trial of 202 patients that compares two different approaches to see if one results in a lower rate and/or intensity of knee pain. One approach is to use a skin incision just below the kneecap (IP); the other involves an incision above (SP). 

Principal Investigator: Dr. Brad Petrisor

Operative versus Non-operative Treatment of Acute Unstable Chest Wall Injuries

This study is a multi-site randomized control trial comparing early surgical fixation versus conventional, non-surgical treatment of unstable chest injuries in 206 patients on the basis of the number of days spent free from a mechanical ventilator in the first 28 days following surgery. 

Principal Investigator: Dr. Brad Petrisor

Reamer Irrigator Aspirator versus Autogenous Iliac Crest bone graft for the Treatment of Non-Unions

This multi-site randomized controlled trial compares two bone graft procedures for the treatment of iliac crest non-unions in 104 patients. The primary objective is to determine if one procedure provides the same quantity and quality of bone graft for the treatment of non-unions, as well as a reduction in post-operative pain and a lower rate of complications as the other procedure.

Principal Investigator: Dr. Brad Petrisor

A Multicentre, Randomized Trial of Far Cortical Locking versus Standard Constructs for Acute, Displaced Fractures of the Distal Femur treated with Locked Plate Fixation

This multi-site randomized controlled trial compares far-cortical locking screws versus standard locking screws for distal femur fractures treated with locking plate fixation in 114 patients. The primary objective is to determine whether far-cortical locking screws increase fracture healing at 3-months post-fixation when compared to a standard locking screw construct. 

Principal Investigator: Dr. Brad Petrisor

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